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Two of the five studies were open-label trials looking at use of aripiprazole for irritability and aggression in either the PDD population or in patients with aggression regardless of underlying diagnosis.
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Schizophrenia is a psychotic disorder (or a group of disorders) marked by severely impaired thinking, emotions, and behaviors.
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The FDA is warning that uncontrollable urges to gamble, binge eat, shop, and have sex are associated with the use of the antipsychotic aripiprazole (Abilify, Abilify Maintena, Aristada).
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Aripiprazole is not indicated for treatment of dementia-related psychosis due to an increased risk of death seen in the elderly.
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Overall, there was little difference in the incidence of discontinuation due to adverse events between aripiprazole-treated (7%) and placebo-treated (9%) patients.
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Current evidence for aripiprazole as augmentation therapy in major depressive disorder.
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The beneficial impact of these drugs is greatest on psychotic symptoms, particularly hallucinations and delusions in the early and midterm stages of the disorder.
As with most psychoactive medications, patients should be advised to avoid alcohol while taking ABILIFY.
This is not a complete list of all side effects that may occur.
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